Vesicular Stomatitis (VS or VSV) is a viral disease that primarily affects cattle, horses, and swine and occasionally sheep, goats, llamas, and alpacas. Humans can also become infected with the disease when handling affected animals, but this is a rare event. The main sign in animals is oral disease appearing as mucosal vesicles and ulcers in the mouth, but also on the udder and around the coronary band. Animals may show systemic signs such as anorexia, lethargy and pyrexia. Disease usually resolves within two weeks, and animals usually recover completely.